April 17, 2018

Pets, Vets, and Opioids

Remaining knowledgeable and observing relevant legal requirements will enable veterinarians to be strong advocates for the responsible use of opioids.
By Carolyn C. Shadle, PhD, and John L. Meyer, PhD
Strange Cast of Dr. Jekyll and Mr. Hyde, written by Robert Louis Stevensen, describes a medical doctor who swallows a potion that transforms him from a rational, intelligent human into an evil monster. Although it was written in 1886, the novella strikes an ominous chord today. Opioids—the modern equivalent of the doctor’s potion—can create dependency, transform people into strangers sometimes given to harmful deeds, and bring on the distinct possibility of death.

Today’s nationwide opioid epidemic is turning families and entire communities upside down. The most recent report from the American Society of Addiction Medicine states that prescription medication overdose is the leading cause of accidental death among people under 50. The group also noted that opioid addiction is driving this epidemic, with over 20,000 overdose deaths related to prescription pain relievers in 2015.1

Opioids in Veterinary Medicine
How does this very human problem relate to the veterinary profession? After all, veterinarians prescribe opioids for animals—period. “They cannot and do not prescribe for people,” said Larry J. Nieman, DVM, co-owner of the veterinary consulting firm Essential Elements. Licensed in 6 states, Dr. Nieman has been a veterinary clinician for 42 years and has had a Controlled Dangerous Substance license from the US Department of Justice Drug Enforcement Administration (DEA). He is past president of the Connecticut Veterinary Medical Society and served on the legislative council of the Oklahoma Medical Association.

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Veterinarians are not a part of the problem, Dr. Nieman said, and they typically do not prescribe the most commonly abused opioids, such as oxycodone and fentanyl.

Still, the opioid epidemic does affect animals, their owners, and even veterinary teams. Recent reports and expert insight show clearly how this crisis affects today's veterinarians.

Abuse Among Pet Owners
The most common opioid carried by veterinary practices and targeted by addicts is tramadol, which is prescribed to both animals and humans. There have been just enough reports of abuse or misuse to cause concern and prompt some states to increase regulations. Last fall, for example, following an investigation by the research firm Aurelius Value, the website Mercola reported that PetMed Express (also known as 1-800-PetMeds) was accused of selling pet opioids for use in people.2 PetMed Express denied the allegation.

Then there is the issue of pet owners supporting their own addictions by taking medications intended for their pets. In a 2017 NBC News report, David Gurzak, DVM, an associate at Brackett Street Veterinary Clinic in Portland, Maine, said that to him, the first sign that something is amiss is when a pet owner asks for a drug by name.3 He recalled a client who repeatedly requested a prescription for tramadol. “It was for a dog that had a condition...that normally would not require any medication at all,” Dr. Gurzak said. “I suspected that she was using it herself.”

Eli Landry, DVM, CVA, owner of Seminole Veterinary Hospital in Oklahoma, reported seeing pet owners coming into the practice looking for opioids for themselves. “Generally,” he said, “it’s a new client we’ve never seen before who comes with an old patient, and they’ll ask for the drugs by name, like ‘Oh, my ailing and aging dog really needs some tramadol for his lame leg.’”3

In a report on Florida’s WPBF News, Lisa Ciucci, DVM, owner of Gardens Animal Hospital in Palm Beach Gardens, Florida, told the reporter about “blacklisted” clients who go from veterinarian to veterinarian seeking medications such as tramadol, Xanax, and Valium by name.4 Some owners give excuses for why they need another refill of pills, such as spilling them on the floor, she said, while others go so far as to physically harm their pets to get a new prescription.

Jim Arnold, chief of policy and liaison for the DEA’s Diversion Control Division, told the New York Post: “They’ve gotten very sophisticated in how they obtain drugs and go about their activities...It’s an area that allows drug seekers to fly under the radar. We know it’s happening, but I wouldn’t be surprised if there’s a lot more activity than we’re aware of.”5
Tramadol, prescribed for both pets and people, is the
opioid carried by veterinary practices.

Marsha Mercer reported in The Washington Post in September 2017, “Last year in Virginia, a dog owner took his boxer to 6 veterinarians to get antianxiety pills and painkillers for his own use before he was caught.” Eventually, according to Fairfax County police, the owner was charged with prescription fraud. Mercer also reported on other cases: “In Kentucky in 2014, a woman was accused of cutting her golden retriever twice with a razor so she could get drugs. And in the early 2000s, an Ohio man allegedly taught his dog to cough on cue so the owner could buy hydrocodone.”6

The Potential for Pet Overdose
Another concern for veterinarians: the risk of accidental opioid overdose in pets. In a bizarre but true story from New Hampshire, a 3-month-old puppy named Zoey ingested an opioid while on a walk with her owner around her neighborhood. Zoey was rushed to the hospital and given naloxone to revive her. The hospital owner, pleased with the outcome, noted that the incident indicates the extent of the opioid crisis.7

Abuse by Veterinary Practice Employees
The rampant abuse of opioids creates yet another risk: staff access to these drugs, according to Kimberly Hammer, VMD, DACVIM (SAIM), a medical director at NorthStar Vets Veterinary Emergency Trauma & Specialty Center in Robbinsville, New Jersey. Checks and balances within a veterinary hospital are essential with respect to ordering, storage, administration, and dispensing for the health and protection of the staff, as well as the legal protection of the doctor and hospital, Dr. Hammer said.

Legal Responses
The opioid epidemic has prompted many states to sign control measures into law. In Maine, for example, professionals—including veterinarians—who can prescribe drugs are required to check a statewide database called the Prescription Monitoring Program (PMP) before prescribing opioids and benzodiazepines. This measure ensures that doctors notify the proper authorities if certain criteria are met when a patient comes in and has reason to leave with opioids.

Other states have variations of the PMP and are passing legislation with more stringent requirements for dispensing and reporting opioid prescriptions. For example, a New Jersey law limits initial opioid prescriptions to a 5-day supply, one of the strictest prescribing limits in the country.8 Pharmacies in the Garden State are required to report prescription data that is shared with 14 other states. Guidelines related to the legislation urge veterinarians who prescribe potentially addictive opioids, such as tramadol and oxycodone, to use the New Jersey PMP.9 Nine other states, including New York and Massachusetts, have legislation that limits opioid prescriptions to 7 days or less.10 A review of current prescription drug abuse legislation in the United States can be found on the National Conference of State Legislatures website.11

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